Archive for October, 2008

Flow FTP client updated

Thursday, October 30th, 2008

Extendmac released an updated version of its FTP client Flow, bringing the current version to 1.1.

The new version offers better error-handling for all protocols, public iDisk support, and more secure WebDAV and MobileMe iDisk authentications. Flow also lets you browse a local disk from the sidebar.

Flow also now supports multi-touch gestures. You can swipe left and right to move backward and forward. Swiping up and down will navigate to the parent directory, or enter the selected directory.

Swipe is available for download and costs $29.

Breast milk provides baby molecule to build immunity

Thursday, October 30th, 2008

A molecule holds the key to mothers’ ability to strengthen the immunity of the baby through breast milk, according to a latest research.

The study highlights the amazing change that takes place in a mother’s body when she begins producing breast milk.

Years before her pregnancy, cells that produce antibodies against intestinal infections travel around her circulatory system and regularly take an “off-ramp” to her intestine.

There they stand guard against infections like cholera or rotavirus. But once she begins lactating, some of these antibody-producing cells suddenly begin taking a different off-ramp that leads to the mammary glands.

That way, when her baby nurses, the antibodies go straight to their intestine and offer protection while the baby builds up its own immunity. This is why previous studies have shown that formula-fed infants have twice the incidence of diarroheal illness as breast-fed infants.

Until now, scientists did not know how the mother’s body signalled the antibody-producing cells to take the different off-ramp. The new study identifies the molecule that gives them the green light.

“Everybody hears that breast feeding is good for the baby,” said Eric Wilson, Brigham Young University microbiologist who is a co-author of the study.

“But why is it good? One of the reasons is that mothers’ milk carries protective antibodies which shield the newborn from infection, and this study demonstrates the molecular mechanisms used by the mother’s body to get these antibody-producing cells where they need to be.”

Understanding the role of the molecule, called CCR10, also has implications for potential future efforts to help mothers better protect their infants, according to a release from the Brigham University.

Wilson’s other co-authors are Yuetching Law, Kathryn Distelhorst and Erica D. Hill.

Harvard Medical School co-authors are Olivier Morteau, Craig Gerard, Bao Lu, Sorina Ghiran and Miriam Rits. Stanford University School of Medicine co-authors are Raymond Kwan, Nicole H. Lazarus and Eugene C. Butcher.

These findings are scheduled for publication in Nov 1 issue of the Journal of Immunology.

Yahoo, AOL in due diligence on combination - source

Thursday, October 30th, 2008

Yahoo Inc and Time Warner Inc’s AOL unit are looking at each other’s books to figure out how much money they could make together and where costs can be saved, a person familiar with the talks said on Wednesday, indicating a merger may finally be on the way.

While noting a deal was not imminent, the source said the two companies have engaged in “meaningful” due diligence about a possible combination for the past couple of weeks.

Talks are focused on how to integrate AOL’s content and advertising business into Yahoo, said the source, who was not authorized to speak publicly because the discussions are confidential.

Yahoo and Time Warner began talks several months ago, when the Internet company was looking for an alternative growth strategy to fend off a $47.5 billion takeover bid from Microsoft Corp.

Yahoo had repeatedly rejected Microsoft, which finally withdrew its $33-per-share proposal in June after Yahoo cut a search advertising partnership with Google Inc.

But the Google deal, also part of Yahoo’s alternative strategy, is mired in the regulatory process because critics have said it is anti-competitive. Meanwhile, Yahoo shares have plunged to around $12.

Time Warner shares are down about 45 percent from year-earlier levels, while Yahoo shares have fallen about 63 percent, as fears of an economic recession curbed corporate spending on advertising while Google continued to dominate in the Web search market.

Under the deal Yahoo and Time Warner have discussed, Yahoo would fold AOL’s content and advertising business into its own operations, and Time Warner would get a stake in the combined company.

Executives and advisers from both sides met last week as part of the due diligence process, the source said. Both sides are being cautious because any potential deal carries “a lot of risk,” the source said, without providing further details.

Integration concerns would likely revolve around how to fold AOL’s advertising network into Yahoo’s operations, choosing whether to keep separate portals and email services, and squeezing out cost savings by reducing duplication, one former AOL executive said on condition of anonymity.

Yahoo and Time Warner declined comment. News of the due diligence was first reported by the AllThingsDigital blog.

Shares of Yahoo were up 4 cents at $12.40 in late trading, while Time Warner shares were down 15 cents or 1.5 percent at $9.95.

American, Russians return from space station

Saturday, October 25th, 2008

A Soyuz capsule carrying an American and two Russians touched down on target in Kazakhstan on Friday after a descent from the international space station, safely delivering the first two men to follow their fathers into space.

The Soyuz TMA-12 capsule landed at 9:37 a.m. local time, about 55 miles north of Arkalyk in north-central Kazakhstan, Russian Mission Control spokesman Valery Lyndin told The Associated Press.

Search and recovery crews buzzed in on Mi-8 helicopters and extracted Richard Garriott, Sergei Volkov and Oleg Kononenko from the capsule, which landed on its side on the brushy surface under a clear sky.

“What a great ride that was,” said Garriott, an American computer game designer who paid some $30 million for a 10-day stay on the space station. Sitting in an armchair and wrapped in a blue blanket against the near-freezing temperature on the steppe, he smiled broadly.

“This is obviously a pinnacle experience,” Garriott said in televised comments.

Garriott was greeted by his father, Owen Garriott, a retired NASA astronaut who flew on the U.S. space station Skylab in 1973.

“Hey, Papa-san,” said Richard Garriott, 47. The pair shook hands.

“How come you look so fresh and ready to go?” Owen Garriott, 77, asked his son.

“Because I’m fresh and ready to go — again,” he replied.

Not right away, though.

“I’m looking forward to some fresh food and to calling my loved ones,” said Garriott, who lives in Austin, Texas, and was seen off by his girlfriend and brother, among others, when he rocketed up to the station on another Soyuz craft on Oct. 12.

“I’ve got my father here, but I’ve got other family back home I want to get a hold of.”

Volkov sat next to Garriott. The son of a cosmonaut, he beat out Garriott as the first human being to follow a parent into space when he flew up to the space station six months ago. Kononenko, who also spent 199 days in space, was the last out of the capsule and could not be seen in the TV footage.

The head of the Russian space agency Roskosmos, Anatoly Perminov, said on state-run Vesti-24 television that Kononenko had a tougher time than his crewmates during the descent but “feels good now.” It was the first space mission for all three men.

The uneventful descent was a relief for space officials — and the crew — after technical problems caused unusually steep “ballistic descents” for the last two returning crews, putting them hundreds of miles off course and subjecting them to stronger gravitational force than in a usual.

On a Soyuz returning in May, the malfunction of an explosive bolt delayed the separation of the re-entry capsule from the rest of the ship. It forced the crew — including a U.S. astronaut and South Korea’s first space traveler — to endure a rough ride as the gyrating capsule descended facing the wrong way.

It took nearly half an hour for search helicopters to locate the capsule, which landed some 20 minutes late and 260 miles off target, and determine the crew was unharmed.

Last October, a computer glitch sent Malaysia’s first astronaut and two Russian cosmonauts on a steeper-than-normal path during their return to Earth.

Russian space officials said changes had been made to equipment and computer programming to prevent another ballistic descent, but they were clearly relieved at Friday’s on-time, on-target landing.

The Soyuz TMA-12’s module separated without a hitch before it entered the atmosphere, and a series of parachutes gradually slowed its speed from 755 feet per second to about 5 feet per second.

“I can’t recall a more ideal landing,” Perminov said.

Garriott, who created the Ultima computer game series, spent time on the station conducting experiments — including some whose sponsors helped pay for a trip he said cost him a large chunk of his wealth. He also took pictures of the Earth’s surface to measure changes since his father did the same 35 years ago.

Garriott took a Soyuz up to the 10-year-old station along with U.S. astronaut Michael Fincke and Russian cosmonaut Yuri Lonchakov, who will stay in orbit for six months. Also on board is U.S. astronaut Gregory Chamitoff.

The U.S. shuttle Endeavor is due to launch in November and carry equipment needed for raising the number of astronauts living at the orbiting outpost from three to six. That transition should occur in the first half of next year.

The head of the Russian state-controlled RKK Energiya company, which builds the Soyuz spacecraft and Progress cargo ships, said Friday that construction of ships for the next few missions was on schedule, but further plans could be jeopardized by a money crunch caused by the nation’s financial crisis. Vitaly Lopota said the banks had been slow to provide loans to the company, and he urged the government to quickly earmark funds.

Depression During Pregnancy May Cause Premature Birth

Friday, October 24th, 2008

Women who are depressed early in their pregnancy run a higher risk of preterm delivery, the leading cause of infant mortality, a new study suggests.

For the study, researchers interviewed 791 San Francisco-area women near their 10th week of pregnancy. Forty-one percent reported “significant” symptoms of depression, and 22 percent reported “severe” symptoms.

Those women with severe symptoms had almost twice the risk of an early birth, defined as before 37 weeks’ gestation. Those with significant symptoms had a 60 percent risk of early birth, the study found.

Women who were likelier to report depressive symptoms tended to be younger than 25, unmarried, less educated, poorer, black, and have a history of preterm delivery.

Discovering a possible cause of preterm birth, about which little is known, makes the findings significant, said study lead author Dr. De-Kun Li, a perinatal epidemiologist and senior research scientist at Kaiser Permanente’s Division of Research in Oakland, Calif.

Scientists have been researching for the causes of high rates of infant mortality in the United States, Li said, but, “we don’t know what is going on. If we can find something as obvious as depression that can be treated during pregnancy, that is very, very significant.”

The findings were published online Oct. 23 in the journal Human Reproduction.

Dr. Shari I. Lusskin, director of reproductive psychiatry at New York University Medical Center, said she doesn’t think the study establishes a link between depression in early pregnancy and preterm delivery. She said the women in the study weren’t clinically diagnosed with depression but had scored high on a screening test.

“We don’t know if the depression at 10 weeks is a marker for something that happens later in pregnancy, which is the real culprit,” she said.

Li hopes the study’s findings will make “ante-natal depression” as widely recognized as postpartum depression has become. Until now, depression during pregnancy has been “under-estimated and under-treated,” he said, “not just by women, but also by their doctors.”

One reason for this lack of attention is that there hasn’t been strong evidence of a connection between depression in pregnant women and harm to the fetus, Li said.

Women may not readily report depressed feelings when they are pregnant because of the societal expectation that having a baby should be a joyous occasion, said Dr. Jennifer Wu, an obstetrician and gynecologist at Lenox Hill Hospital in New York City.

“I think many patients are very stressed about pregnancy and worried about the pregnancy and not sure about its impact on their lives,” Wu said.

Lusskin tries to spread the word about the dangers of depression during pregnancy.

“The more we know about postpartum depression, the more we realize that half the cases started in pregnancy,” Lusskin said. Ante-natal depression also carries the risk of noncompliance with prenatal care, poor nutrition, inadequate sleep, self-medication with drugs and alcohol, and suicide, she explained.

And, Lusskin added, “Ante-natal depression interferes with bonding with the baby both during pregnancy and post-partum.”

The take-home lesson from the Kaiser study, Lusskin said, “is that ante-natal depression and ante-natal depression symptoms have some effect on pregnancy, and they should be treated, even though we don’t know how that mood is translated into the biochemistry of that pregnancy.”

She added that she is “a proponent of maintaining a good mood throughout pregnancy and breast-feeding, and doing what you have to do to do that. If a patient requires medication, she should do that. Then, it’s a matter of finding the drugs that are best studied and most effective for the patient.”

Lufthansa bids for Austrian Airlines, but deal in doubt

Friday, October 24th, 2008

German airline Deutsche Lufthansa AG has submitted a valid bid for Austrian Airlines AG (AUA), the country’s takeover watchdog confirmed Thursday, but it said it was still uncertain if there would be a deal.

The Austrian government holding OeIAG is in the process of selling its 42.75 percent stake in the country’s ailing flag carrier.

‘Against the background of AUA’s economic development and an apparent wide gap between the negotiating positions, it is uncertain whether the transaction can be concluded,’ the Austrian Takeover Commission said in a statement.

Air France dropped out of the bidding process Tuesday, and the commission’s statement did not make any mention that the third suitor, the Russian carrier S7 Airlines, had submitted a valid offer by the deadline on Tuesday.

The German carrier has time until Friday to make a final price proposal.

On Monday, the OeIAG holding is set to consider the offer.

According to analysts, Lufthansa is unlikely to pay the 5 euros or 7 euros ($6.44-9) per share reported in Austrian media, given that the takeover candidate has debts worth 800 million euros.

The takeover commission made its statement after having told the Vienna stock exchange Thursday morning to stop trading in Austrian Airlines shares, which had lost 30.2 percent of their value Wednesday.

In the first half-hour after trading resumed in the afternoon, shares rose to 3.07 euros, a gain of 7.7 percent.

Because of the free-fall in the shares Thursday, Lufthansa would have been obliged under Austrian takeover rules to inform the authorities of its bid already on Wednesday, commission head Stefan Arnold said.

Last week, the management of Austrian Airlines issued a warning that the company would end the year with a deficit of 125 million euros ($168 million), mainly as a result of high fuel costs.

Coffee exports in first quarter see increase in unit value realisation

Friday, October 24th, 2008

Coffee exports in the first quarter of the current fiscal (2008-09) marked an increase in quantity, value and unit value realisation as compared to the same period a year ago. Exports of the commodity during the first quarter stood at 62,000 tonne valued at Rs 242.49 crore, an analysis by the United Planters’ Association of Southern India (Upasi) said. Exports had a unit value realisation of Rs 23.58 per kg, it said.

Indian coffee exports witnessed a resurgence in terms of value realisation last fiscal (2007-08). There was an increase in value realisation by Rs 30.96 crore in spite of declining exports, which stood at 2,49,000 tonne in 2006-07 to 2,18,000 tonne in 2007-08, the analysis said. Unit value realisation per kg of coffee exported last fiscal was higher by Rs 12.73 pr kg as against the previous year.

Exporters were able to transact and ship out maximum quantity of the commodity in the last quarter, thereby offsetting a decline in export quantum during the first three quarters, the study revealed. This helped derive maximum advantage from higher global prices during that period in time.

The gloabl coffee price movement pattern was comparable to the price realisation at domestic auctions, the Upasi study said, adding that this was along expected lines as the export orientation of the Indian coffee sector was at a high of 75%. World exports of coffee declined from 95.4 million bags in fiscal 2007 to 90.6 million bags in 2008, down by 4.8 million bag. Domestic coffee production for 2007-08 was down by 26,000 tonne from 2,62,000 tonne as against 2,88,000 tonne in the previous year, Upasi said. The post-blossom survey indicated that India’s coffee crop in the current fiscal would touch 293,000 tonne, which is higher by 31,000 tonne compared to the production last year.

The decline in production in 2007-08 was on account of a drop in Robusta by 10%.

US military deaths in Iraq war at 4,186

Thursday, October 23rd, 2008

at least 4,186 members of the U.S. military have died in the Iraq war since it began in March 2003, according to an Associated Press count.

The figure includes eight military civilians killed in action. At least 3,387 military personnel died as a result of hostile action, according to the military’s numbers.

The AP count is two fewer than the Defense Department’s tally, last updated Wednesday at 10 a.m. EDT.

The British military has reported 176 deaths; Italy, 33; Ukraine, 18; Poland, 21; Bulgaria, 13; Spain, 11; Denmark, seven; El Salvador, five; Slovakia, four; Latvia and Georgia, three each; Estonia, Netherlands, Thailand and Romania, two each; and Australia, Hungary, Kazakhstan and South Korea, one death each.

LA councilman seeks to halt zoo elephant exhibit

Thursday, October 23rd, 2008

Bob Barker, Alicia Silverstone and other celebrities are joining a city councilman’s effort to move elephants from the Los Angeles Zoo to a massive sanctuary where they can roam free — or at least close to it.

Councilman Tony Cardenas, accompanied by several celebrities at a news conference Tuesday, announced his desire to halt construction of the zoo’s elephant habitat and use the money to build a 60-acre sanctuary operated by the zoo.

“We need to get those elephants out of the LA Zoo,” Cardenas said.

Cardenas filed two motions Tuesday at the City Council meeting to reallocate what’s left of the $39 million approved for the elephant exhibit and open the sanctuary in the northern San Fernando Valley. He said the 3 1/2-acre “Pachyderm Forest” at the zoo will be too small to keep elephants happy and healthy.

Los Angeles Zoo officials said they intend to complete the project, which will house 11 African elephants and a breeding program. Zoo director John Lewis said construction is one-third complete and about $10.2 million has been spent.

Cardenas said he was one of the council members who approved the new facility in 2006, but “ever since then, it really hasn’t set well with me.”

Cardenas said he decided the city’s elephant exhibit needed drastic changes after visiting Ruby, a former zoo elephant, at the Performing Animal Welfare Society sanctuary in Stockton.

“You could see in her eyes, she looked healthy. She was interacting with the other elephants,” he said.

At the news conference, which included celebrity animal lovers Barker, Silverstone, Robert Culp and Esai Morales, the councilman played a video of the zoo’s only pachyderm, Billy. The elephant was seen bobbing his head — a behavior that animal advocates say is caused by the psychological stress of living in confinement.

Barker said Cardenas’ proposal is “the perfect solution” for Billy and other elephants scheduled to arrive at the zoo.

Lewis defended the zoo’s care of the elephant, saying Billy bobs his head when zoo personnel come to feed or care for him.

“Is it a normal elephant behavior? No. Is it pathological? No. It’s a Billy behavior,” Lewis said.

Cardenas said a sanctuary would cost $10 million. The unfinished elephant habitat at the zoo could be turned over to giraffes, saving the city $20 million, he said.

A City Council panel will review the proposal Nov. 6.

Indicted over Darfur, Sudan’s President Feints and Punches Back

Thursday, October 23rd, 2008

Ever since the International Criminal Court began pursuing allegations of war crimes in Darfur in 2005, its investigators have pursued a government-backed militia leader known as “the colonel of colonels.” Ali Muhammad Ali Abd Al Rahman - a.k.a. Ali Kushayb - was high in the pantheon of the Janjaweed militia when a warrant was finally issued for his arrest in February 2007. Investigators said he led raids that left hundreds dead and countless homes destroyed. According to one witness, Ali Kushayb once inspected a line of naked women just before they were raped by his men. There were critical grumblings that the Sudanese government was coddling him: Ali Kushayb had been detained before but had been released for lack of evidence.

So it was more than a surprise when Khartoum announced last week that it had, in fact, been holding Ali Kushayb for several months and that he would be put on trial. “The timing of this particular claim about an arrest is certainly interesting,” says Christopher Hall, head of Amnesty International’s International Justice Project. Sudan claims that the investigation into Kushayb gained speed after a special prosecutor was appointed in August. But Hall and many others suspect that Ali Kushayb’s trial - if it ever happens - is just the Sudanese government’s latest gambit in what has become a full-blown campaign to derail the International Criminal Court’s investigation into its own complicity in charges of genocide in Darfur.

“We haven’t actually seen anything formal,” Hall says of Ali Kushayb’s trial. “One of the things that Amnesty International is asking for immediately is that Sudan permit a trial observer to attend the proceedings and for a copy of the charges and any other court documents related to the case.” On Tuesday, the New York-based Human Rights Watch derided Sudan’s domestic investigations into the Darfur conflict as nothing more than “window dressing.” The group’s Africa director, Georgette Gagnon, said that Sudan was clearly trying to block the ICC’s work. “No one should be fooled by these moves,” she said in a statement released on the group’s web site.

The government of President Omar al-Bashir has been criticized for its methods and policies since the very start of the Darfur conflict, which has killed some 300,000 and displaced 2.5 million in five years. Along with domestic trials, which have achieved little, Bashir announced on Thursday a “people’s initiative” to bring peace to Darfur, even though none of the rebel groups agreed to take part.

Such gestures have come more frequently in recent months as Sudan tries to shut down the ICC investigations, experts say. For a couple of years, Sudan seemed to have regarded the Hague-based International Criminal Court dismissively, but its focus was sharpened in July when Chief Prosecutor Luis Moreno-Ocampo sought an arrest warrant for President Bashir himself. During the annual General Assembly session last month, Sudan pressed its case with other countries. The Bashir government warned that Sudan could cancel all its agreements with the U.N. if the ICC case goes ahead. “It is not true that the government is trying to show the world they are trying to do something - in fact, they are doing something,” Sudanese Foreign Ministry spokesman Ali Sadiq Ali told TIME. However, just for good measure, he repeated the government’s stance that “it will not hand over a Sudanese citizen to the outside.”?]

The core of Sudan’s strategy is simple. The ICC may only take on cases of war crimes and crimes against humanity if the country where the crimes allegedly occurred doesn’t pursue the cases itself. Since the ICC got the Darfur docket in 2005, Sudan has repeatedly assured the outside world - not very persuasively, experts say - that it is trying Darfur atrocities cases itself. The ICC itself remains unconvinced that Ali Kushayb’s arrest, or Sudan’s prosecution of low-level officials in Darfur, is sincere. “No cases involving serious violations of international humanitarian law have been tried and therefore our case is still admissible and the arrest warrants must be executed,” says Florence Olara, a spokeswoman in the ICC’s prosecutor office.

Bashir has tried to woo African Union leaders, who have a tendency to close ranks around colleagues who become the target of accusations of rights abuses or political shenanigans. And so far, it has worked. The African Union has asked the U.N. Security Council to order the ICC to suspend its Darfur investigations on the grounds that they pose a threat to international peace and security. African Union leaders also say that by prosecuting Bashir, the ICC will complicate matters for U.N. peacekeepers in Darfur, most of whom are from neighboring countries on the continent. Bashir attempts to stall the mission have already left it severely hobbled. “We are simply concerned with the best possible sequencing of measures so that the most immediate matters of saving lives and easing the sufferings of the people of Darfur are taken care of first,” Tanzania’s President Jakaya Kikwete, the current AU chairman, told the U.N. General Assembly in September.

This campaign against the ICC allows Bashir to give the impression that he’s in control. But some experts say the attacks may be a bid to shift attention from his own troubles. Sudanese society, including the government, is not monolithic and it’s important to bear in mind that there are significant divisions in government about how to deal with the war crimes and crimes against humanity in Darfur,” says Hall of Amnesty International. “I wouldn’t be at all surprised if at some point, sooner rather than later, Bashir is arrested by Sudanese police and put on a plane to the Hague.”